Santorini appeared in eight games for the St. Louis Cardinals in 1973, tossing only 8.1 innings and not factoring in a decision while he posted an earned run average of 5.40.
That would be the end of his Big League career, originally coming up as a 20-year-old in 1968 when he appeared in a game for the Atlanta Braves before moving on to the San Diego Padres during their inaugural season.
That year he saw the most action of any season in the Majors, going 8-14 with an ERA of 3.95 over 32 appearances, 30 of them starts, in 184.2 innings of work.
All told, he finished his Major League tenure with a record of 17-38, with an ERA of 4.29 over 127 appearances and 493.1 innings pitched, with four shutouts and three saves.